Promoting greater cooperation, collaboration, innovation, and access.
Home to iconic and growing brands like UPS, Yum! Brands, Humana, Churchill Downs, and Brown-Forman Corporation, Greater Louisville has an impressive portfolio of home-grown companies, globally recognized corporations, and startups. No matter the size or stage of development, Fortune 500 companies and startups alike benefit from our region’s supportive entrepreneurial culture, business-forward thinking, outstanding quality of life, and central, strategic location.
The region is built around six key industry clusters — advanced manufacturing, automotive, defense & aerospace, food and beverage, life sciences, and logistics — which are bolstered by a shared desire to drive innovation through organizations like the Health Innovation Alliance, Amplify, FirstBuild, and One Louisville’s Advanced Manufacturing and Logistics Network and TechFirst Network.
In 2025, One Louisville landed 41 projects representing more than 2,700 new jobs and $3 billion in direct economic investment across 15 counties. But not only are new businesses investing in Greater Louisville, existing employers are doubling down on their investment and expanding their holdings in the region. Ford Motor Company announced a historic $2.2 billion investment retooling the Ford Louisville Assembly Plant to produce Ford’s new line of universal electric vehicles (UEVs) and reinviting how vehicles are assembled, from the historic assembly line into a new and innovative assembly tree model that reduces costs and increases efficiency. Ford has had a long-time presence in Greater Louisville and continues to make the region a central part of its manufacturing and logistics supply chain. GE Appliances, a Haier Company, also announced a $490 million investment to create the world’s most advanced laundry manufacturing line at their global headquarters in Louisville Appliance Park, reshoring production from China and creating 800 new jobs.